Mirghani O A, Saeed O K, Basama F M
MRCOG, Lond.
East Afr Med J. 1992 Aug;69(8):445-9.
Fifty pregnant women with viral hepatitis were compared with 31 non-pregnant women with viral hepatitis in a prospective case-control study. The two groups were matching except for the serum bilirubin level and area of residence. Seven pregnant women died while none of the control patients died and the difference between the two groups was significant. More than 80% of the deaths occurred in the third trimester and most of them were post-partum deaths. Except for a higher incidence of pre-term birth, the outcome of pregnancy in the case group was not affected. It is concluded that pregnancy is a risk factor which increases the mortality of viral hepatitis and that viral hepatitis does not affect the outcome of pregnancy except for pre-term birth.
在一项前瞻性病例对照研究中，对50名患有病毒性肝炎的孕妇与31名非孕病毒性肝炎患者进行了比较。除血清胆红素水平和居住地区外，两组在其他方面进行了匹配。7名孕妇死亡，而对照组患者无一人死亡，两组之间的差异具有显著性。超过80%的死亡发生在孕晚期，其中大多数为产后死亡。除早产发生率较高外，病例组的妊娠结局未受影响。结论是，妊娠是增加病毒性肝炎死亡率的一个危险因素，除早产外，病毒性肝炎不影响妊娠结局。
