Ferguson M A
Department of Biochemistry, University of Dundee, U.K.
Biochem Soc Trans. 1992 May;20(2):243-56. doi: 10.1042/bst0200243.
Over the last few years we have learned of a new type of membrane anchorage for cell-surface proteins, the GPI anchors. We now have a good idea of their structure and biosynthesis, and indications of their specific functions in protozoa and mammals. The widespread distribution of GPI membrane anchors throughout the eukaryotes has led many researchers to work on various aspects of GPI anchors. This has led to the widespread exchange of data, ideas and techniques which has made the field a pleasure to work in.
在过去几年里，我们了解到一种用于细胞表面蛋白的新型膜锚定方式——糖基磷脂酰肌醇（GPI）锚。现在我们对其结构和生物合成有了较为清晰的认识，并且知晓了它们在原生动物和哺乳动物中的特定功能。GPI膜锚在整个真核生物中广泛分布，这促使许多研究人员致力于GPI锚的各个方面的研究。这也带来了数据、想法和技术的广泛交流，使得这个领域成为一个令人愉快的工作领域。
