SCHANE H P, LEONARD S L
Science. 1963 May 17;140(3568):811-2. doi: 10.1126/science.140.3568.811.
Injection of ethylenediaminetetraacetic acid into spayed rats or its use in phosphorylase extraction increases the activity of glycogen-phosphorylase a in uterine smooth muscle tissue. Since the total phosphorylase activity is not increased, the increase in phosphorylase a appears to result from a conversion of inactive phosphorylase b to the active form of the enzyme.
向切除卵巢的大鼠注射乙二胺四乙酸或在磷酸化酶提取过程中使用乙二胺四乙酸,可增加子宫平滑肌组织中糖原磷酸化酶a的活性。由于总磷酸化酶活性并未增加,磷酸化酶a的增加似乎是由无活性的磷酸化酶b转化为该酶的活性形式所致。