SKINNER W A, ALAUPOVIC P
Science. 1963 May 17;140(3568):803-5. doi: 10.1126/science.140.3568.803.
Oxidation of dl-alpha-tocopherol or its model, 6-hydroxy-2,2,5,7,8-pentamethylchroman, with alkaline ferricyanide yields a variety of products. In addition to the known dimeric keto ether, two new products, compound A, a trimer, and compound B, an isomer of compound A, were ioslated. Ultraviolet and infrared absorption spectra and paper chromatography indicate that compound A might be identical with liver metabolite "O" which results from the addition of alpha-tocopherol to the diet.
dl-α-生育酚或其模型化合物6-羟基-2,2,5,7,8-五甲基色满用碱性铁氰化物氧化会产生多种产物。除了已知的二聚体酮醚外，还分离出了两种新产物，三聚体化合物A和化合物A的异构体化合物B。紫外和红外吸收光谱以及纸色谱分析表明，化合物A可能与饮食中添加α-生育酚后产生的肝脏代谢物“O”相同。
