Graham T P, Johns J A
Vanderbilt University School of Medicine, Division of Pediatric Cardiology, Nashville, Tennessee.
Herz. 1992 Aug;17(4):213-9.
In 1978 Choussat and Fontan established ten criteria, which should be fulfilled to achieve a successful outcome in Fontan operation. Recent data suggest that while some of these ten criteria need not be necessarrily be fulfilled, new criteria should be added. These include 1. good diastolic function, 2. normal or only slightly increased ventricular mass, and 3. absence of systemic outflow obstruction. In addition the morphology of the single ventricle may be important as long-term results in patients with single ventricle of right ventricular morphology may be worse than results in patients with single ventricle of left ventricular morphology. Ventricular size and pump function can be assessed by cardiac catherization, echocardiography or magnetic resonance imaging. Estimation of ejection fraction under stress by nuclear angiography may be indicated. Diastolic function can be examined using Doppler echocardiography or nuclear angiography. Myocardial mass may be assessed by echocardiography or magnetic resonance imaging. Normal reference values for different parameters of systolic and diastolic function are listed in the enclosed tables. Patients scheduled for a Fontan operation should have an ejection fraction less than 50%. Patients with borderline ejection fraction should be examined by echocardiography to determine the end-systolic wall stress, a parameter of ventricular contraction, which is independent of pre- and afterload. As afterload may decrease after a Fontan operation some patients with reduced ejection fraction but normal end-systolic wall stress may still be suitable candidates for Fontan operation.(ABSTRACT TRUNCATED AT 250 WORDS)
1978年,乔萨特和丰坦制定了十条标准,丰坦手术若要取得成功就应满足这些标准。近期数据表明,虽然这十条标准中的某些标准不一定必须满足,但应增加一些新的标准。这些新标准包括:1. 舒张功能良好;2. 心室质量正常或仅略有增加;3. 不存在体循环流出道梗阻。此外,单心室的形态可能也很重要,因为右心室形态单心室患者的长期结果可能比左心室形态单心室患者的结果更差。心室大小和泵功能可通过心导管检查、超声心动图或磁共振成像进行评估。可能需要通过核素血管造影术评估应激状态下的射血分数。舒张功能可使用多普勒超声心动图或核素血管造影术进行检查。心肌质量可通过超声心动图或磁共振成像进行评估。收缩和舒张功能不同参数的正常参考值列于随附表格中。计划进行丰坦手术的患者射血分数应低于50%。射血分数处于临界值的患者应通过超声心动图检查以确定收缩末期壁应力,这是心室收缩的一个参数,独立于前负荷和后负荷。由于丰坦手术后后负荷可能降低,一些射血分数降低但收缩末期壁应力正常的患者仍可能是丰坦手术的合适候选人。(摘要截选至250词)