SAKS N M, ROTH C A
Science. 1963 Jul 5;141(3575):46-7. doi: 10.1126/science.141.3575.46.
Morphological changes at the cell level have been produced experimentally by a pulsed ruby laser (optical maser). A pulse duration of approximately 500 microseconds caused discrete damage to structures in the cell without irreversible damage to the surrounding area.