无痤疮痣。

An acne-free naevus.

作者信息

Cunliffe W J, Ead R D, Perera W H, Hodgins M B

出版信息

Br J Dermatol. 1977 Mar;96(3):287-90. doi: 10.1111/j.1365-2133.1977.tb06139.x.

DOI:10.1111/j.1365-2133.1977.tb06139.x

Abstract

Investigation of rare disorders may sometimes help in the understanding of common problems. We describe a patient with an unusual and previously unreported acne-free naevus occurring in an area severely affected by acne. Investigation revealed smaller sebaceous glands, a reduced sebum excretion rate, decreased number of Corynebacterium acnes in the pilosebaceous ducts and a reduced conversion of testosterone to 5 alphadihydrotestosterone in the areas which were free of acne compared with acne-bearing skin. The results of these investigations support some of the suggested mechanisms responsible for the development of acne.

摘要

对罕见疾病的研究有时有助于理解常见问题。我们描述了一名患者，其在严重受痤疮影响的区域出现了一种不寻常且此前未报道过的无痤疮痣。研究发现，与有痤疮的皮肤相比，在无痤疮区域皮脂腺较小、皮脂分泌率降低、毛囊皮脂腺导管中痤疮丙酸杆菌数量减少以及睾酮向5α - 二氢睾酮的转化减少。这些研究结果支持了一些关于痤疮发病机制的推测。