Sinha S, Sinha U, Kangarloo H, Huang H K
Department of Radiological Sciences, School of Medicine, University of California, Los Angeles.
Invest Radiol. 1992 Oct;27(10):856-64. doi: 10.1097/00004424-199210000-00017.
To synthesize magnetic resonance images (MRI) in real-time using a minimal data set obtained with routine clinical protocols and stored in a picture archiving and communication system (PACS) database.
Analytic solutions for T1 and T2 were obtained from a double and a single spin-echo set, with routine parameters. Analytic solutions from radio frequency-spoiled gradient-echo images, with TRs as low as 33 mseconds, also were used to synthesize gradient-echo images.
Phantom studies showed that the errors in the synthesized images were significantly smaller than the errors in the T1- and T2-calculated images and similar to the source images. The gradient-echo images resulted in significant scan time savings.
MRI synthesis from analytic solutions of T1, T2, and rho saves computational time and yields accurate values for the intrinsic parameters while allowing the use of routine clinical protocols. The availability of clinical images in the PACS database and the ability to synthesize images in real-time has allowed the development of a practical interactive teaching module.
使用通过常规临床方案获取并存储在图像存档与通信系统（PACS）数据库中的最小数据集实时合成磁共振成像（MRI）。
从具有常规参数的双自旋回波集和单自旋回波集中获得T1和T2的解析解。还使用了重复时间（TR）低至33毫秒的射频扰相梯度回波图像的解析解来合成梯度回波图像。
模型研究表明，合成图像中的误差明显小于T1和T2计算图像中的误差，且与源图像相似。梯度回波图像显著节省了扫描时间。
从T1、T2和ρ的解析解合成MRI可节省计算时间，并为固有参数产生准确值，同时允许使用常规临床方案。PACS数据库中临床图像的可用性以及实时合成图像的能力促成了一个实用的交互式教学模块的开发。
