Mueller P O, Morris D D, Carmichael K P, Henry M M, Baker J J
Department of Large Animal Medicine, College of Veterinary Medicine, The University of Georgia, Athens 30602.
J Am Vet Med Assoc. 1992 Sep 15;201(6):899-901.
A 10-year-old Tennessee Walking Horse gelding was admitted to the veterinary teaching hospital for evaluation of intermittent fever, lethargy, and anorexia. Initial laboratory analyses revealed anemia and hyperfibrinogenemia. Abdominocentesis and thoracentesis yielded fluid samples with high nucleated cell counts and total protein concentrations. The tentative diagnosis was nonseptic peritonitis. The horse did not improve after 4 days of antimicrobial treatment, and pitting edema of the ventral midline developed. Thoracic radiography and ultrasonography revealed consolidation of the ventral aspect of the lung fields and pleural effusion. Pleuroscopy of the right hemithorax revealed pleural effusion and a soft-tissue mass in the caudal portion of the mediastinum. Findings on biopsy of the liver and mediastinal mass led to a presumptive diagnosis of metastatic cholangiocellular carcinoma. The horse was euthanatized, and the diagnosis was confirmed at necropsy.
一匹10岁的田纳西走马公马被送往兽医教学医院，以评估间歇性发热、嗜睡和厌食症状。初步实验室分析显示贫血和高纤维蛋白原血症。腹腔穿刺术和胸腔穿刺术获取的液体样本中有高核细胞计数和总蛋白浓度。初步诊断为非感染性腹膜炎。经过4天的抗菌治疗后，这匹马没有好转，并且腹中线出现了凹陷性水肿。胸部X光和超声检查显示肺野腹侧出现实变和胸腔积液。右半胸的胸腔镜检查显示胸腔积液和纵隔尾部有一个软组织肿块。肝脏和纵隔肿块活检结果导致转移性胆管细胞癌的初步诊断。这匹马被实施安乐死，尸检时确诊。
