van der Woerdt A, Nasisse M P, Davidson M G
Department of Companion Animal and Special Species Medicine, College of Veterinary Medicine, North Carolina State University, Raleigh 27606.
J Am Vet Med Assoc. 1992 Sep 15;201(6):921-6.
During a 5-year period, phacolytic uveitis was diagnosed in 202 eyes of 151 dogs admitted to the veterinary teaching hospital. The diagnosis of phacolytic uveitis was based on the finding of a cataractous lens and anterior uveitis, unassociated with other identifiable causes of uveal inflammation. The most commonly affected breeds were the Toy and Miniature Poodle (35%) and the American Cocker Spaniel (19%). The mean age was 7.0 years for all breeds, 5.1 years for the Cocker Spaniel, and 9.0 years for the Poodle breeds. Evidence of cataract resorption was visible in 72% of the eyes. Fifty-one dogs were affected bilaterally and 100 dogs unilaterally. The mean interval between recognition of the cataract and the onset of lens-induced uveitis (LIU) was 17 months; mean times of 25 and 11 months were seen in the Poodle breeds and American Cocker Spaniel, respectively. The mean age of dogs requiring greater than 1 revisit before the inflammation had subsided was 5.5 years. Complications, referable to the uveitis, were seen in 14% of eyes, the most important of which were glaucoma (16 eyes) and phthisis bulbi (9 eyes). Lens extraction surgery was done on 50 LIU-affected eyes, and on 35 normal eyes in LIU-affected animals. The 2- and 6-month success rates for LIU-affected eyes were 78 and 39%, respectively, and for normal eyes in LIU-affected animals were 85 and 71%, respectively.(ABSTRACT TRUNCATED AT 250 WORDS)
在5年期间,对收治于兽医教学医院的151只犬的202只眼睛诊断为晶状体溶解性葡萄膜炎。晶状体溶解性葡萄膜炎的诊断基于发现白内障晶状体和前葡萄膜炎,且与其他可识别的葡萄膜炎症原因无关。最常受影响的品种是玩具贵宾犬和迷你贵宾犬(35%)以及美国可卡犬(19%)。所有品种的平均年龄为7.0岁,可卡犬为5.1岁,贵宾犬品种为9.0岁。72%的眼睛可见白内障吸收的迹象。51只犬双眼患病,100只犬单眼患病。从识别白内障到晶状体诱导性葡萄膜炎(LIU)发作的平均间隔时间为17个月;贵宾犬品种和美国可卡犬分别为25个月和11个月。炎症消退前需要不止一次复诊的犬的平均年龄为5.5岁。14%的眼睛出现了与葡萄膜炎相关的并发症,其中最重要的是青光眼(16只眼)和眼球痨(9只眼)。对50只患LIU的眼睛以及患LIU动物的35只正常眼睛进行了晶状体摘除手术。患LIU眼睛的2个月和6个月成功率分别为78%和39%,患LIU动物正常眼睛的成功率分别为85%和71%。(摘要截选至250字)