早期人胎盘分离细胞对4-¹⁴C-脱氢表雄酮和4-¹⁴C-4-雄烯-3,17-二酮的代谢
Metabolism of 4-14C-dehydroepiandrosterone and 4-14C-4-androstene -3, 17-dione by isolated cells of early human placenta.
作者信息
Dziadkowiec I, Czarnik Z
出版信息
Endocrinol Exp. 1977 Mar;11(1):19-22.
PMID:140044
Abstract
The preparation of isolated cells was used for the study of the metabolism of 4-14C-dehydroepiandrosterone and 4-14C-4-androstene-3,17-dione in early human placenta. Free cells suspension converted dehydroepiandrosterone and 4-androstene-3,17-dione into estrone, estradiol-17beta and into C1[neutral steroids 4-androstene-3,17-dione and testosterone.
摘要
分离细胞的制备用于研究早期人胎盘中4-¹⁴C-脱氢表雄酮和4-¹⁴C-4-雄烯-3,17-二酮的代谢。游离细胞悬液将脱氢表雄酮和4-雄烯-3,17-二酮转化为雌酮、雌二醇-17β以及C1[中性类固醇4-雄烯-3,17-二酮和睾酮。
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