一名患有Y;13易位的不育男性的临床及减数分裂研究。

Clinical and meiotic studies in an infertile man with Y;13 translocation.

作者信息

Micic M, Nikolis J, Micic S

机构信息

Institute of Biology and Human Genetics, Faculty of Medicine, Belgrade, Yugoslavia.

出版信息

Hum Reprod. 1992 Sep;7(8):1118-20. doi: 10.1093/oxfordjournals.humrep.a137804.

DOI:10.1093/oxfordjournals.humrep.a137804

PMID:1400936

Abstract

Clinical and meiotic studies were done on an infertile man with a translocation between Yq and 13q, who was identified through the birth of his son with partial trisomy 13q. Seminal plasma transferrin showed preserved Sertoli cell function while lactate dehydrogenase C4 indicated hypospermatogenesis. A quadrivalent in diakinesis and spermatogenic arrest in the second meiotic division was detected.

摘要

对一名不育男性进行了临床和减数分裂研究，该男性Yq与13q之间存在易位，通过其患有部分13q三体综合征的儿子出生而被发现。精浆转铁蛋白显示支持细胞功能保留，而乳酸脱氢酶C4表明精子发生减少。在终变期检测到一个四价体，在第二次减数分裂中存在生精停滞。