Bauwens J E, Spach D H, Schacker T W, Mustafa M M, Bowden R A
Fred Hutchinson Cancer Research Center, Seattle, Washington 98104.
J Clin Microbiol. 1992 Sep;30(9):2474-5. doi: 10.1128/jcm.30.9.2474-2475.1992.
Bordetella bronchiseptica is a frequent cause of respiratory infections in animals but rarely causes disease in humans. We describe a patient with B. bronchiseptica pneumonia and bacteremia that developed following bone marrow transplantation. B. bronchiseptica infection persisted despite antimicrobial therapy and may have progressed because of the combined effects of the patient's underlying immunosuppression and the antimicrobial antagonism between doxycycline and ciprofloxacin.
支气管败血波氏杆菌是动物呼吸道感染的常见病因，但很少导致人类发病。我们描述了一名在骨髓移植后发生支气管败血波氏杆菌肺炎和菌血症的患者。尽管进行了抗菌治疗，支气管败血波氏杆菌感染仍持续存在，可能由于患者潜在的免疫抑制以及强力霉素和环丙沙星之间的抗菌拮抗作用共同影响而病情进展。
