Ackermann G L, Altini M
University of the Witwatersrand, Johannesburg.
J Dent Assoc S Afr. 1992 May;47(5):187-94.
The aim of this study was to assess whether sub-classification of cemental tumors was warranted and to define the clinicopathological features of the definitive entities. Our sample consisted of 127 cases which were divided into the following categories; gigantiform cementoma (84 per cent), cementifying fibroma (12 per cent), benign cementoblastoma (4 per cent). Gigantiform cementoma lesions were either single, multiple or florid and ranged in size from 1 to 10 cm. Most occurred in patients in their 6th and 7th decades who were black (78 per cent) and female (96 per cent). All lesions showed typical solid sheets of acellular cementum and some (22 per cent) were characterised by peripheral proliferative areas which were often indistinguishable from lesions of cementifying fibroma and periapical cemental dysplasia. Infection and sequestration was very common (54 per cent). No cases of periapical cemental dysplasia were found and we suggest that this lesion is a variant of gigantiform cementoma. We believe cementifying fibroma to be part of the histomorphological spectrum of cemento-ossifying fibroma. Cemento-osseous dysplasia is a more accurate and appropriate term than gigantiform cementoma and we recommend the following classification for cemental 'tumors': cemento-ossifying fibroma; cementoblastoma; cemento-osseous dysplasia, single, multiple and florid sub-types.
本研究的目的是评估牙骨质瘤的亚分类是否合理,并确定各明确实体的临床病理特征。我们的样本包括127例病例,分为以下几类:巨大型牙骨质瘤(84%)、牙骨质化纤维瘤(12%)、良性成牙骨质细胞瘤(4%)。巨大型牙骨质瘤病变可为单发、多发或弥漫性,大小从1至10厘米不等。大多数发生在60和70多岁的患者中,患者多为黑人(78%)和女性(96%)。所有病变均显示典型的无细胞牙骨质实性片,部分病变(22%)的特征为周边增殖区,这些增殖区常与牙骨质化纤维瘤和根尖周牙骨质发育异常的病变难以区分。感染和死骨形成非常常见(54%)。未发现根尖周牙骨质发育异常病例,我们认为该病变是巨大型牙骨质瘤的一种变异型。我们认为牙骨质化纤维瘤是牙骨质骨化纤维瘤组织形态学谱系的一部分。与巨大型牙骨质瘤相比,牙骨质骨发育异常是一个更准确和恰当的术语,我们建议对牙骨质“肿瘤”进行以下分类:牙骨质骨化纤维瘤;成牙骨质细胞瘤;牙骨质骨发育异常,包括单发、多发和弥漫性亚型。