Saito M, Wei B R, Furukawa K, Konaka C, Kato H, Ebihara Y
Department of Surgery, Tokyo Medical College, Japan.
Nihon Kyobu Geka Gakkai Zasshi. 1992 Sep;40(9):1788-91.
This patient, a 62-year-old female, with squamous cell carcinoma of the lung was inoperable because of poor pulmonary function due to severe bronchial stenosis by a tumor at the orifice of the right main bronchus. As the tumor decreased in size after photodynamic therapy (PDT), the bronchial stenosis decreased and her pulmonary function improved sufficiency to permit surgery. When right upper sleeve lobectomy was performed, only limited peribronchial inflammation related to PDT procedure was detected indicating only slight extrabronchial influence of PDT. This suggests that PDT is a viable adjunct modality in case in which surgery might possible be performed. The patient has a good postoperative course and is alive 18 months after surgery without any evidence of recurrence.
该患者为62岁女性，患有肺鳞状细胞癌，因右主支气管开口处肿瘤导致严重支气管狭窄，肺功能较差，无法进行手术。在光动力疗法（PDT）后肿瘤体积缩小，支气管狭窄减轻，肺功能改善到足以允许手术。行右上叶袖状肺叶切除术时，仅检测到与PDT操作相关的有限的支气管周围炎症，表明PDT对支气管外的影响较小。这表明在可能进行手术的情况下，PDT是一种可行的辅助治疗方式。该患者术后恢复良好，术后18个月仍存活，无任何复发迹象。
