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99mTc-HMPAO脑单光子发射计算机断层扫描在颅外颈动脉病变中的应用:颈动脉内膜切除术后缺血区域变化的评估

Cerebral SPECT with 99mTc-HMPAO in extracranial carotid pathology: evaluation of changes in the ischemic area after carotid endarterectomy.

作者信息

Saccà A, Pedrini L, Vitacchiano G, Pisano E, Zagni P, Bellanova B, Dondi M, Monetti N

机构信息

Chair of Vascular Surgery, University of Bologna, Italy.

出版信息

Int Angiol. 1992 Apr-Jun;11(2):117-21.

PMID:1402215
Abstract

The authors report their experience in studying patients undergoing carotid endarterectomy with simple photon emission computed tomography (SPECT). This technique made it possible to identify areas of preoperative cerebral hypoperfusion in 54.8% of the patients which had a good correlation with neurological symptoms. To distinguish gradual changes in the ischemic lesions, a method of assessing the surface of the hypoperfused areas was adopted. In addition, SPECT made it possible to detect a greater number of hypoperfused areas even in sites other than those revealed by CT. Moreover, there was good correlations between the SPECT data and the grade and site of the carotid lesion and the data provided by some intraoperative monitoring procedures. The Authors therefore propose the use of SPECT in the evaluation of patients with cerebrovascular insufficiency following a carotid disease.

摘要

作者报告了他们使用单光子发射计算机断层扫描(SPECT)研究接受颈动脉内膜切除术患者的经验。这项技术能够在54.8%的患者中识别出术前脑灌注不足的区域,这些区域与神经症状有良好的相关性。为了区分缺血性病变的逐渐变化,采用了一种评估灌注不足区域表面的方法。此外,SPECT即使在CT显示区域以外的部位也能检测到更多的灌注不足区域。而且,SPECT数据与颈动脉病变的分级和部位以及一些术中监测程序提供的数据之间存在良好的相关性。因此,作者建议将SPECT用于评估患有颈动脉疾病后脑血管功能不全的患者。

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