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囊性神经母细胞瘤。

Cystic neuroblastoma.

作者信息

Croitoru D P, Sinsky A B, Laberge J M

机构信息

Department of Pediatric General Surgery, Montreal Children's Hospital, McGill University, Quebec, Canada.

出版信息

J Pediatr Surg. 1992 Oct;27(10):1320-1. doi: 10.1016/0022-3468(92)90286-g.

DOI:10.1016/0022-3468(92)90286-g
PMID:1403512
Abstract

In the newborn, cystic masses of the adrenal gland are unusual findings and most are secondary to hemorrhage. We present a patient with a clinical history typical for adrenal hemorrhage who was found to have a thick walled cystic adrenal mass on both physical and ultrasound examination. During evaluation the mass decreased in size, but vanillylmandelic acid (VMA) and homovanillic acid (HVA) levels were elevated. Laparotomy and left adrenalectomy confirmed the diagnosis of a cystic neuroblastoma. Adrenal cyst, adrenal abscess, and cystic neuroblastoma are all rare entities in the newborn. We recommend that all cystic masses of the adrenal be evaluated by urinary VMA and HVA and that the possibility of cystic neuroblastoma be kept in mind when an adrenal cystic mass is followed nonoperatively.

摘要

在新生儿中,肾上腺囊性肿块是不常见的发现,大多数是由出血继发引起的。我们报告一例具有典型肾上腺出血临床病史的患者,其在体格检查和超声检查中均发现有壁厚的肾上腺囊性肿块。在评估过程中,肿块大小减小,但香草扁桃酸(VMA)和高香草酸(HVA)水平升高。剖腹手术及左肾上腺切除术确诊为囊性神经母细胞瘤。肾上腺囊肿、肾上腺脓肿和囊性神经母细胞瘤在新生儿中均为罕见疾病。我们建议对所有肾上腺囊性肿块进行尿VMA和HVA评估,并且在对肾上腺囊性肿块进行非手术随访时应考虑到囊性神经母细胞瘤的可能性。

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引用本文的文献

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A prospective study of expectant observation as primary therapy for neuroblastoma in young infants: a Children's Oncology Group study.一项针对小婴儿神经母细胞瘤期待观察作为一线治疗的前瞻性研究:一项儿童肿瘤协作组研究。
Ann Surg. 2012 Oct;256(4):573-80. doi: 10.1097/SLA.0b013e31826cbbbd.
2
Bilateral adrenal cystic neuroblastoma with superior vena cava syndrome and massive intracystic haemorrhage.双侧肾上腺囊性神经母细胞瘤伴上腔静脉综合征及大量囊内出血。
Pediatr Radiol. 2004 Sep;34(9):746-9. doi: 10.1007/s00247-004-1209-5. Epub 2004 May 26.