Welch C C
Postgrad Med. 1977 May;61(5):138-44. doi: 10.1080/00325481.1977.11712190.
Alcohol has been suspected for many years of being a cause of heart disease. For a while its role was obscured by its association with beriberi heart disease and, more recently, by the toxic effect of cobalt in beer. Experimental studies, however, have provided convincing evidence of the primary role of alcohol itself. The mode of action is still in dispute. In the absence of specific findings, the diagnosis is made chiefly by exclusion of other known causes of heart disease and by a history of excessive alcohol intake over a number of years. The usual methods of treatment for the manifestations of heart failure, arrhythmias, and thromboembolic phenomena are important, but total abstinence from alcohol is the single essential factor. The sooner this is instituted, the better is the chance of interrupting the otherwise inexorable course to death.
多年来,酒精一直被怀疑是心脏病的病因。有一段时间,它的作用因与脚气性心脏病的关联而被掩盖,最近又因啤酒中钴的毒性作用而受到影响。然而,实验研究提供了令人信服的证据,证明酒精本身起主要作用。其作用方式仍存在争议。在没有具体发现的情况下,诊断主要通过排除其他已知的心脏病病因以及多年过量饮酒史来做出。针对心力衰竭、心律失常和血栓栓塞现象的常规治疗方法很重要,但完全戒酒是唯一的关键因素。越早开始戒酒,中断否则将不可避免地走向死亡的进程的机会就越大。