Carpenter R, Royle G T, Cross M, Hamilton C, Buchanan R, Taylor I
University Surgical Unit, Royal South Hants Hospital, Southampton.
J R Soc Med. 1992 Aug;85(8):454-6. doi: 10.1177/014107689208500810.
After breast conservation for early breast cancer which comprised wide local excision, axillary clearance and radiotherapy to the breast, 145 women have been followed prospectively for a median of 42 months. Local recurrence occurred in 11 (7%) and axillary recurrence in three (2%). Distant recurrence has occurred in 32 and accounted for 80% of all first recurrences. Local treatment failure has occurred in three women and would not have been prevented by mastectomy. Loco-regional recurrence in the absence of preceding or synchronous distant disease was unusual and did not pose a significant clinical problem.
对145名接受早期乳腺癌保乳治疗（包括广泛局部切除、腋窝清扫和乳房放疗）的女性进行了中位时间为42个月的前瞻性随访。局部复发11例（7%），腋窝复发3例（2%）。远处复发32例，占所有首次复发的80%。3名女性出现局部治疗失败，乳房切除术无法预防这种情况。无前驱或同步远处疾病时的局部区域复发并不常见，也未构成重大临床问题。
