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[杂种犬急性小肠缺血的实验病理学研究——用球囊导管阻塞肠系膜前动脉近端部位]

[An experimental pathologic study of acute small intestinal ischaemic in mongrel dogs--occluded proximal site of anterior mesenteric artery by balloon catheter].

作者信息

Atari E, Mitomi H, Kan T, Kusano S, Okudaira M

机构信息

Department of Pathology, School of Medicine, Kitasato University.

出版信息

Nihon Shokakibyo Gakkai Zasshi. 1992 Aug;89(8):1491-8.

PMID:1404977
Abstract

We prepared experimental of small intestinal ischemia by occluding the inlet of the anterior mesenteric artery of adult mongrel dogs with balloon catheters. With these experimental models, the degree of tissue damage of the small intestinal mucosa, which became ischemic, was studied according to the different occlusion times of the anterior mesenteric artery (3, 5, 7, 10, 15 and 30 hours). As a result, ischemic mucosal lesions in the small intestine at an initial stage occurred on the antimesenteric side. In the gross findings of the mucosa when the occlusion time was within 5 hours, linear and spotted lesions appeared in a zone on the antimesenteric side. When the occlusion time was 7 hours or more, these lesions fused and the entire intestinal mucosa became a hemorrhagic lesion. By occluding the anterior mesenteric artery for 22-30 hours, all 6 experimental ischemic animals died.

摘要

我们通过用球囊导管阻塞成年杂种犬肠系膜前动脉入口来制备小肠缺血实验。利用这些实验模型,根据肠系膜前动脉不同的阻塞时间(3、5、7、10、15和30小时),研究发生缺血的小肠黏膜的组织损伤程度。结果,小肠缺血性黏膜病变最初发生在系膜对侧。当阻塞时间在5小时以内时,黏膜大体观察可见系膜对侧区域出现线状和点状病变。当阻塞时间为7小时或更长时,这些病变融合,整个肠黏膜变成出血性病变。通过阻塞肠系膜前动脉22 - 30小时,6只实验性缺血动物全部死亡。

相似文献

3
Superior mesenteric artery occlusion in dogs: a model to produce the spectrum of intestinal ischemia.
J Surg Res. 1975 Oct;19(4):251-7. doi: 10.1016/0022-4804(75)90089-x.

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