两例伴有红细胞形态改变的血栓性血小板减少性紫癜
TWO CASES OF THROMBOHAEMOLYTIC THROMBOCYTOPENIC PURPURA ASSOCIATED WITH CHANGES IN RED CELL MORPHOLOGY.
作者信息
MCCORMACK P, O'BRIEN D J, OLIVER R A
出版信息
J Clin Pathol. 1963 Sep;16(5):436-40. doi: 10.1136/jcp.16.5.436.
Abstract
Two adult cases of thrombohaemolytic thrombocytopenic purpura are described. Both showed striking morphological changes in the red cells with increased saline osmotic fragility, in addition to thrombocytopenia and generalized hyaline thrombi affecting small blood vessels. These changes support the hypothesis that this is a triple auto-immune disorder affecting red cells, platelets, and small blood vessels.
摘要
本文描述了两例成人血栓性血小板减少性紫癜病例。除血小板减少以及累及小血管的全身性透明血栓形成外，两例患者的红细胞均呈现出显著的形态学改变，且盐水渗透脆性增加。这些改变支持了以下假说：这是一种影响红细胞、血小板和小血管的三重自身免疫性疾病。
Zotero 插件