Offret G, Dhermy P, Offret H, Cardozo S
Arch Ophtalmol (Paris). 1976 Nov;36(11):709-32.
A composite review of 24 cases of embryonal rhabdomyosarcoma which is seen in fact to be the commonest orbital malignant tumour in children. In its evolution, most often very rapid, sometimes pseudo-inflammatory, this tumour presents many different histological appearances among which the alveolar form and the botryoidal form should be particularly distinguished. Although it was for a long time confused with reticulosarcoma the tumour is in fact derived from primitive undifferentiated mesenchymal cells and can therefore in this sense be considered as a blastoma. Since the prognosis is grave and its treatment often disappointing, it should in many cases combine surgery with radiotherapy and polychemotherapy.
对24例胚胎性横纹肌肉瘤的综合回顾,实际上这种肿瘤是儿童最常见的眼眶恶性肿瘤。在其发展过程中,通常进展非常迅速,有时呈假炎症性,该肿瘤呈现出许多不同的组织学表现,其中肺泡型和葡萄状型应特别加以区分。尽管长期以来它与网状细胞肉瘤相混淆,但实际上该肿瘤起源于原始未分化的间充质细胞,因此从这个意义上讲可被视为母细胞瘤。由于预后严重且治疗往往不尽人意,在许多情况下应将手术与放疗及多药化疗相结合。