大鼠的长期隔离应激
LONG-TERM ISOLATION STRESS IN RATS.
作者信息
WIBERG G S, GRICE H C
出版信息
Science. 1963 Oct 25;142(3591):507. doi: 10.1126/science.142.3591.507.
PMID:14064449
Abstract
Rats isolated for long periods became nervous and aggressive and developed caudal dermatitis ( scaly tail). After 13 weeks of isolation, rats had heavier adrenals and thyroid and lighter spleen and thymus compared with rats kept in community cages. This indicates an endocrinopathy with hyperfunction of the adrenal cortex.
摘要
长期隔离的大鼠变得紧张、好斗，并出现尾部皮炎（尾巴鳞片化）。与饲养在群居笼中的大鼠相比，隔离13周后的大鼠肾上腺和甲状腺更重，脾脏和胸腺更轻。这表明存在肾上腺皮质功能亢进的内分泌病。
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