Goertz B, Kunst H
Fortschr Neurol Psychiatr Grenzgeb. 1977 Feb;45(2):106-11.
The case of a 42-year-old female patient with central disturbance of respiration was reported which, contrary to the previously described forms of central alveolar hypoventilation, could be characterized by paroxysmal-like apnoic conditions without any feeling of suffocation. Clinically, initial cardiopulmonary complications were primary in this central disturbance of respiration. The possibility of isolated apnoic paroxysms as an expression of a true cerebro-organic nature of the attacks was described. In addition, the attempt was made to localize the morphological or functional disturbance at the basis of the observed pathological process in the bulbopontine area of the brain stem on the ventral side of the medulla in the area of the point of exit of the seventh to the twelfth cranial nerves. With anticonvulsive and analeptic treatment, a distinct improvement could be observed in the disease after the cardiopulmonary complications had subsided.
报告了一例42岁女性患者，其存在中枢性呼吸障碍，与先前描述的中枢性肺泡低通气形式不同，其特征为阵发性呼吸暂停，且无任何窒息感。临床上，在这种中枢性呼吸障碍中，最初的心肺并发症是主要的。描述了孤立性呼吸暂停发作作为发作真正脑器质性本质表现的可能性。此外，试图根据在脑干延髓腹侧第七至第十二对脑神经出口区域观察到的病理过程，定位形态学或功能障碍。经过抗惊厥和兴奋治疗，在心肺并发症消退后，病情有明显改善。
