KADIS S, AJL S J, RUST J H
J Bacteriol. 1963 Oct;86(4):757-65. doi: 10.1128/jb.86.4.757-765.1963.
Kadis, Solomon (Albert Einstein Medical Center, Philadelphia, Pa.), Samuel J. Ajl, and James H. Rust, Jr. Action of plague murine toxin on mitochondria from resistant and susceptible animals. J. Bacteriol. 86:757-765. 1963.-Purified murine Pasteurella pestis toxin inhibited the respiration of liver mitochondria isolated from both the rat and the rabbit. Toxin had little or no effect on the respiration of rabbit sarcosomes, but when they were disrupted with either sodium deoxycholate or sonic vibration their respiration was inhibited. The respiration of heart mitochondria from rats immunized with toxoid-adjuvant mixtures was inhibited only slightly by the toxin, whereas the respiration of liver mitochondria from immunized rats was inhibited to the same degree as that from nonimmunized animals. Toxin caused the heart mitochondria of the rat to swell, but had little or no effect on the heart mitochondria of the rabbit. Also, brain mitochondria were not swollen by the toxin.
卡迪斯，所罗门（宾夕法尼亚州费城阿尔伯特·爱因斯坦医疗中心），塞缪尔·J·阿吉尔，小詹姆斯·H·拉斯特。鼠疫鼠毒素对耐药和敏感动物线粒体的作用。《细菌学杂志》86:757 - 765。1963年。——纯化的鼠疫耶尔森氏菌鼠毒素抑制了从大鼠和兔子分离的肝线粒体的呼吸作用。毒素对兔肌粒的呼吸作用几乎没有影响，但当它们用脱氧胆酸钠或超声振动破坏后，其呼吸作用受到抑制。用类毒素 - 佐剂混合物免疫的大鼠心脏线粒体的呼吸作用仅受到毒素的轻微抑制，而免疫大鼠的肝线粒体的呼吸作用受到的抑制程度与未免疫动物相同。毒素导致大鼠心脏线粒体肿胀，但对兔子的心脏线粒体几乎没有影响。此外，毒素不会使脑线粒体肿胀。
