[氢化可的松对主动脉中酸性粘多糖组成部分的影响]
[Effect of hydrocortisone on the fractional makeup of acid mucopolysaccharides in the aorta].
作者信息
Khomulo O S, Konnova L A
出版信息
Biull Eksp Biol Med. 1976 Aug;82(8):956-7.
PMID:140714
Abstract
Five components of the acid mucopolysaccharides were isolated from rabbit aorta; these were hyaluronic acid, heparitin sulphate, chondroitin sulphate A, C and B. Prolonged administration of hydrocortisone increased the hyaluronic acid concentrations and decreased the level of heparitin sulphate. Fifteen days after the cessation of the hormone administration the aortic tissue proved to contain a lower percentage of chondroitin sulphate A, C anc B.
摘要
从兔主动脉中分离出酸性粘多糖的五种成分；它们是透明质酸、硫酸类肝素、硫酸软骨素A、C和B。长期给予氢化可的松会增加透明质酸的浓度，并降低硫酸类肝素的水平。停止给予激素15天后，主动脉组织中硫酸软骨素A、C和B的百分比降低。
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