Altman D G, Irwig L M, Jagdish V
Bull Eur Physiopathol Respir. 1977 Mar-Apr;13(2):281-4.
In many circumstances it may not be possible to measure peak expiratory flow rate on all subjects using the same meter. A small trial was carried out to assess the variability of such meters. Five newly calibrated adult Wright peak expiratory flow meters, which gave comparable readings when rechecked on another rotameter, were compared in a trial on 160 schoolchildren. Each child blew once into each meter, and the design was balanced so that the effect of order of blow was eliminated. Statistically significant differences were found between the meters, although the difference between any pair of meters was less than 5% of the average peak flow rats. Since the meters were chosen because they were very similar it is likely that larger differences would be found in other circumstances. This could be an important source of error in multicentre studies where several meters have to be used.
在许多情况下,可能无法使用同一台仪器对所有受试者测量呼气峰值流速。开展了一项小型试验以评估此类仪器的变异性。在一项针对160名学童的试验中,比较了五台新校准的成人赖特呼气峰值流速仪,这些仪器在另一台转子流量计上重新检测时给出了可比读数。每个孩子对着每台仪器吹一次气,设计采用了平衡法,从而消除吹气顺序的影响。尽管任意两台仪器之间的差异小于平均峰值流速的5%,但仍发现仪器之间存在统计学上的显著差异。由于选择这些仪器是因为它们非常相似,所以在其他情况下可能会发现更大的差异。这可能是多中心研究中一个重要的误差来源,因为在多中心研究中必须使用多台仪器。