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[年轻患者的脑缺血]

[Cerebral ischemia in young patients].

作者信息

Mrówka R, Pieniazek J, Hendryk S, Szydlik W, Słowiński J

机构信息

Katedry i Kliniki Neurochirurgii i Neurotraumatologii, Bytomiu SL AM, Katowicach.

出版信息

Neurol Neurochir Pol. 1992;Suppl 1:83-8.

PMID:1407333
Abstract

The clinical, angiographic and computed tomography (CT) examinations of 19 patients aged from 12 to 30 years with signs of ischaemic brain syndrome are presented. On the basis of these examinations and data obtained from literature it is supposed that in a majority of patients the disease is caused by basal arteriopathies + i.e. pathological changes in the wall of cerebral arteries, mainly of the circulus Willis. The features distinguishing this syndrome from ischaemic disease in adults are presented and discussed. These are first of all: sudden onset connected with physical effort, deep neurological deficit, narrowing or occlusion of basal cerebral arteries seen in angiography and signs of ischaemia within deep cerebral structures visible in CT. The methods of treatment are discussed, mainly STA-MCA anastomosis used in most cases. The results of treatment are discussed. Finally the problem of the cerebral ischaemic syndrome in young people is presented from the point of view of haemodynamics, principally in the aspect of haemodynamic reserve of cerebral blood flow.

摘要

本文介绍了19例年龄在12至30岁之间有缺血性脑综合征体征患者的临床、血管造影和计算机断层扫描(CT)检查情况。基于这些检查以及从文献中获得的数据推测,大多数患者的疾病是由基底动脉病变引起的,即脑动脉壁的病理变化,主要是 Willis 环的病变。文中介绍并讨论了该综合征与成人缺血性疾病相区别的特征。首先是:与体力活动相关的突然起病、严重的神经功能缺损、血管造影显示基底脑动脉狭窄或闭塞以及CT可见深部脑结构内的缺血迹象。文中讨论了治疗方法,多数情况下主要采用颞浅动脉-大脑中动脉吻合术。讨论了治疗结果。最后从血流动力学角度,主要是脑血流动力学储备方面,阐述了年轻人脑缺血综合征的问题。

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