被大量用碘-131标记的抗原对抗体的抑制作用
ANTIBODY SUPPRESSION BY ANTIGEN HEAVILY LABELED WITH IODINE-131.
作者信息
WEBBER M M
出版信息
Science. 1964 Jan 10;143(3602):132-3. doi: 10.1126/science.143.3602.132.
PMID:14075720
Abstract
Antibody formation in rabbits was suppressed by tobacco mosaic virus heavily labeled with iodine-131. Animals were injected intravenously with virus containing 0.5 to 4.4 mc of l(131) and after a period of 6 days were challenged with a new antigen, gammaglobulin. Most irradiated animals did not produce detectable antibody. No signs of radiation sickness were noted.
摘要
用碘 - 131高度标记的烟草花叶病毒抑制了兔体内抗体的形成。给动物静脉注射含有0.5至4.4微居里碘 - 131的病毒，6天后用新抗原γ球蛋白进行攻击。大多数受照射的动物未产生可检测到的抗体。未观察到辐射病的迹象。
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