Actis Dato A, Chiusolo C, Cicchitti G C, Actis Dato G M, Porro M C, Bello A
Università degli Studi di Chieti, Cattedra di Cardiochirurgia, Istituzione Italiana di Cardiochirurgia-Torino.
Minerva Cardioangiol. 1992 Jun;40(6):225-9.
Bacterial endocarditis on cardiac valvular prosthesis is still a frequent and dangerous complication: septicemia, embolism, valvular dysfunction and mortality. To prevent these complications, intraoperative treatment of prosthesis, by immersion in antibiotic solution, was performed in 1262 patients. The postoperative results have been compared with results of a nontreated group. The incidence of endocarditis in the treated group was 1.3%, in non-treated cases 5.45%. The cases of early endocarditis, was 0.08% of total cases of complications in the treated patients group; and 4.54% in the nontreated patient group. This study's results, confirm the utility of valvular prosthesis antibiotic treatment in cardiac surgery.
心脏瓣膜人工假体上的细菌性心内膜炎仍然是一种常见且危险的并发症，包括败血症、栓塞、瓣膜功能障碍和死亡。为预防这些并发症，对1262例患者的人工假体进行了术中抗生素溶液浸泡治疗。将术后结果与未治疗组的结果进行了比较。治疗组心内膜炎的发生率为1.3%，未治疗组为5.45%。早期心内膜炎病例在治疗患者组并发症总数中占0.08%；在未治疗患者组中占4.54%。本研究结果证实了心脏手术中瓣膜人工假体抗生素治疗的有效性。
