Mehta J, Wang Y, Lawrence C, Cohn J N
Chest. 1977 Jun;71(6):784-6. doi: 10.1378/chest.71.6.784.
Ventricular septal defect is sometimes associated with aortic regurgitation. In this report, an echocardiogram demonstrating dramatic prolapse of the noncoronary cusp into the left ventricular outflow tract and ventricular septal defect in a patient with Down's syndrome and ventricular septal defect, confirmed by angiographic studies, is presented. The echocardiogram supports the concept of anatomic lack of support of the aortic ring due to a deficient septum and hemodynamically significant flow of blood to the right ventricle through the ventricular septal defect, resulting in trauma to aortic cusps and prolapse.
室间隔缺损有时与主动脉瓣关闭不全相关。在本报告中，展示了一名患有唐氏综合征和室间隔缺损患者的超声心动图，经血管造影研究证实，其非冠状动脉瓣叶显著脱垂至左心室流出道并伴有室间隔缺损。超声心动图支持了由于间隔缺损导致主动脉环解剖学支撑不足的概念，以及血液通过室间隔缺损向右心室的血流动力学显著分流，从而导致主动脉瓣叶创伤和脱垂。
