Bleiberg H, Rozencweig M, Gangii D, Heuson J C
Endoscopy. 1976 Nov;8(4):217-20. doi: 10.1055/s-0028-1098419.
Two cases of breast cancer are presented in which massive liver metastases were proved by biopsies prior to treatment. Use of alternate cyclical hormonal cytotoxic combination chemotherapy (EORTC Clinical Trial, protocol, no 10741/3) was followed by a dramatic disappearance of neoplastic tissue. Peritoneoscopy associated with needle biopsy proved extremely useful to provide objective evaluation of the response to chemotherapy.
本文报告两例乳腺癌患者，在治疗前经活检证实有大量肝转移。采用交替周期性激素细胞毒性联合化疗（欧洲癌症研究与治疗组织临床试验，方案编号10741/3）后，肿瘤组织显著消失。腹腔镜检查联合针吸活检被证明对化疗反应的客观评估极为有用。
