Tomezsko J L, Stallings V A, Scanlin T F
Department of Pediatrics, Hahnemann University Hospital, Philadelphia, PA 19102-1192.
Pediatrics. 1992 Oct;90(4):547-53.
Because a low calorie intake may result in growth failure and malnutrition in patients with cystic fibrosis (CF), the dietary and energy intakes of 22 children with CF who had mild lung disease and excellent Shwachman scores were examined and compared with those of 23 normal control subjects similar in age (5 to 10 years), gender, and weight. The children with CF consumed significantly more calories than the control subjects. Calorie intake was 111 +/- 19.9% (mean +/- SD) of estimated requirements (World Health Organization recommendations) for the CF group and 97 +/- 18.7% for the control group (P = .014). Calories consumed per kilogram of body weight were 117% of World Health Organization (CF) vs 97% (control) (P = .009). Calorie intake compared to the 1989 Recommended Dietary Allowance was 106 +/- 20.6% for the CF group vs 93 +/- 19.1% for the control group. Fat consumed as a percent of total calories was similar: 33.5% (CF) vs 32.2% (control). All children with CF had pancreatic insufficiency and, on average, consumed a large number of pancreatic enzyme supplements, resulting in dietary fat absorption of 86 +/- 12%. It is concluded that these children with CF were able to maintain normal growth and energy stores on a diet that was relatively high in calories compared to control subjects and moderate in percent fat, along with an aggressive pancreatic enzyme supplement regimen.
由于低热量摄入可能导致囊性纤维化（CF）患者生长发育不良和营养不良，因此对22名患有轻度肺部疾病且Shwachman评分优异的CF儿童的饮食和能量摄入进行了检查，并与23名年龄（5至10岁）、性别和体重相似的正常对照受试者进行了比较。CF儿童摄入的热量明显高于对照受试者。CF组的热量摄入量为估计需求量（世界卫生组织建议）的111±19.9%（平均值±标准差），对照组为97±18.7%（P = 0.014）。每千克体重摄入的热量，CF组是世界卫生组织建议量的117%，而对照组为97%（P = 0.009）。与1989年推荐膳食摄入量相比，CF组的热量摄入量为106±20.6%，对照组为93±19.1%。脂肪占总热量的百分比相似：CF组为33.5%，对照组为32.2%。所有CF儿童均有胰腺功能不全，平均服用大量胰酶补充剂，膳食脂肪吸收率为86±12%。研究得出结论，与对照受试者相比，这些CF儿童能够通过摄入相对高热量且脂肪百分比适中的饮食，以及积极的胰酶补充方案，维持正常生长和能量储备。
