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Recombinant erythropoietin as treatment for the late hyporegenerative anemia of Rh hemolytic disease.

作者信息

Ohls R K, Wirkus P E, Christensen R D

机构信息

Division of Human Development and Aging, University of Utah School of Medicine, Salt Lake City.

出版信息

Pediatrics. 1992 Nov;90(5):678-80.

PMID:1408538
Abstract

Infants with Rh hemolytic disease can develop a "late" anemia characterized by low serum concentrations of erythropoietin but erythroid progenitors that remain highly erythropoietin-responsive. Erythropoietin administration was evaluated in two patients as an alternative to transfusion. Reticulocyte counts increased after 5 days of treatment, and hematocrits increased after 10 days. Neither patient received erythrocyte transfusions following erythropoietin therapy.

摘要

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