Ivanova V V, Aksenov O A, Kvetnaia A S, Kurbatova G P, Bulovskaia L N, Kamal'dinova E G, Govorova L V, Osipova Z A, Blagoslovenskiĭ G S
Pediatriia. 1992(4-6):8-12.
Clinical and laboratory criteria for estimating the role of viruses and bacteria that determine bronchopulmonary diseases have been derived. The clinical importance of the detectable microflora, part of which permanently invade the nasopharynx (pneumococcus, adenoviruses) is under critical review. Pneumonias that may develop within the first days of acute respiratory viral infection are characterized by monoviral influenzal or RS-infection; later pneumonias are marked by viral infection with the predominance of adenoviruses. Attempt has been made to reveal the role of geno- and phenotypic factors (N-acetylation, lipid peroxidation, synthesis of alpha-interferon). The data obtained support an assumption about self-regulation of the child's immune system and the adaptation character of responses in mixed infections.
已经得出了用于评估决定支气管肺部疾病的病毒和细菌作用的临床及实验室标准。对可检测到的微生物群落的临床重要性进行了批判性审查，其中一部分微生物群落会持续侵入鼻咽部（肺炎球菌、腺病毒）。急性呼吸道病毒感染最初几天内可能发生的肺炎，其特征为单病毒流感或呼吸道合胞病毒感染；后期肺炎则以腺病毒占主导的病毒感染为特征。已尝试揭示基因和表型因素（N - 乙酰化、脂质过氧化、α - 干扰素合成）的作用。所获得的数据支持了关于儿童免疫系统自我调节以及混合感染中反应的适应性特征的假设。
