RUBIN A L, STENZEL K H, HIRSCHHORN K, BACH F
Science. 1964 Feb 21;143(3608):815-6. doi: 10.1126/science.143.3608.815.
Cultures of peripheral lymphocytes may be used to assay histocompatibility. The lymphocytes from potential kidney recipients are cultured with those from potential donors and the percentage of large cells and mitoses stimulated is determined. The immunologic competence of cultured lymphocytes from recipients receiving immunosuppressive therapy is evaluated by determining their responsiveness to phytohemagglutinin. Suppression of response appears to be correlated with the absence of clinical signs of graft rejection.
外周淋巴细胞培养可用于检测组织相容性。将潜在肾移植受者的淋巴细胞与潜在供者的淋巴细胞一起培养，然后测定被刺激的大细胞和有丝分裂的百分比。通过测定接受免疫抑制治疗的受者培养淋巴细胞对植物血凝素的反应性来评估其免疫能力。反应受抑制似乎与无移植排斥的临床体征相关。
