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Immunology. 1963 Nov;6(6):513-9.
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FURTHER STUDIES OF EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS IN THE FOWL. 3. THE ENCEPHALOPATHIC EFFECT OF HOMOLOGOUS AND HETEROLOGOUS ALLERGENS, AND THE SUSCEPTIBILITY OF DIFFERENT LINES IN A CLOSED FLOCK.家禽实验性变应性脑脊髓炎的进一步研究。3. 同种和异种变应原的脑病变效应，以及封闭鸡群中不同品系的易感性
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2
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Rapid Production of Acute Disseminated Encephalomyelitis in Rhesus Monkeys by Injection of Brain Tissue With Adjuvants.用佐剂注射脑组织在恒河猴中快速产生急性播散性脑脊髓炎。
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Tuberculin type sensitivity to spinal cord antigen in rabbits with isoallergic encephalomyelitis.同种变应性脑脊髓炎家兔对脊髓抗原的结核菌素型敏感性。
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Clinico-pathologic correlations in experimental allergic encephalomyelitis. II. Development of an index for quantitative assay of encephalitogenic activity of antigens.实验性变应性脑脊髓炎的临床病理相关性。II. 抗原致脑脊髓炎活性定量测定指标的建立。
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Allergic neuritis: an experimental disease of rabbits induced by the injection of peripheral nervous tissue and adjuvants.变应性神经炎：一种通过注射周围神经组织和佐剂诱发的兔实验性疾病。
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The efficacy of the intracutaneous route of injection and the susceptibility of the Hartley strain of guinea pigs in experimental allergic encephalitis.
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禽类实验性变应性脑脊髓炎的进一步研究。II. 剂量变化对组织学损伤的影响。

FURTHER STUDIES OF EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS IN THE FOWL. II. THE INFLUENCE OF DOSE VARIATIONS ON THE HISTOLOGICAL LESIONS.

作者信息

WIGHT P A, SILLER W G

出版信息

Immunology. 1963 Nov;6(6):513-9.

PMID:14088889
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1423342/
Abstract

The effects of varying the dose of the constituents of an inoculum known to produce EAE in a reciprocal cross of Brown Leghorn fowls have been studied. Large amounts of the emulsifying agent suppressed the severity of the histological lesions. Fifty mg. of homologous spinal cord and 2 mg. of per bird were found to be the optimum doses necessary to produce consistently severe histological lesions. A standard procedure for inducing EAE for quantitative studies in `B×I' Brown Leghorn fowls was adopted.

摘要

在来航鸡的正反交中，研究了改变已知能诱发实验性变态反应性脑脊髓炎（EAE）的接种物成分剂量所产生的影响。大量乳化剂可抑制组织学损伤的严重程度。发现每只鸡50毫克同源脊髓和2毫克是持续产生严重组织学损伤所需的最佳剂量。采用了一种在“B×I”来航鸡中诱导EAE进行定量研究的标准程序。