Opolski G, Putkiewicz K, Stolarz P, Kraska T
Kliniki Kardiologii Instytutu Chorób Wewnetrznych AM, Warszawie.
Pol Arch Med Wewn. 1992 Jun;87(6):352-7.
This study evaluated the relation between patency of the infarct related artery and the presence of ventricular late potentials (VLP) on the signal-averaged electrocardiogram (ECG). 44 patients (pts) after myocardial infarction (MI) (35 men, 9 women; mean age 50 years) were studied by coronary angiography. measurement of ejection fraction and signal-averaged ECG. The infarct-related artery was closed in 15 pts and open in 29 pts. There was no difference in age, previous MI and location of infarct between the two study groups. Thrombolytic therapy in acute stage of MI was significantly often (p less than 0.05) in pts with open (59%) than closed (13%). The incidence of VLP was significantly higher (p less than 0.05) in group of pts with closed (40%) than open artery (7%). These data indicate that patency of the infarct-related artery has a beneficial effect on the electrophysiologic substrate for serious ventricular arrhythmias.
本研究评估了梗死相关动脉通畅情况与信号平均心电图（ECG）上室性晚电位（VLP）之间的关系。对44例心肌梗死（MI）患者（35例男性，9例女性；平均年龄50岁）进行了冠状动脉造影、射血分数测量及信号平均心电图检查。梗死相关动脉在15例患者中闭塞，在29例患者中通畅。两个研究组在年龄、既往心肌梗死情况及梗死部位方面无差异。梗死相关动脉通畅的患者（59%）在心肌梗死急性期接受溶栓治疗的比例显著高于动脉闭塞的患者（13%）（p<0.05）。梗死相关动脉闭塞组患者VLP的发生率（40%）显著高于动脉通畅组（7%）（p<0.05）。这些数据表明，梗死相关动脉通畅对严重室性心律失常的电生理基质具有有益作用。
