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醋酸皮质醇诱导幼鼠消瘦症

WASTING DISEASE INDUCED IN YOUNG MICE BY ADMINISTRATION OF CORTISOL ACETATE.

作者信息

SCHLESINGER M, MARK R

出版信息

Science. 1964 Feb 28;143(3609):965-6. doi: 10.1126/science.143.3609.965.

Abstract

A single injection of cortisol acetate into young mice induced a wasting syndrome similar to that observed in runt disease and in the post-thymectomy syndrome. The course of the disease was less severe if the dose of the drug was decreased or if the animals were older at the time of injection.

摘要

对幼鼠单次注射醋酸皮质醇会诱发一种消瘦综合征,类似于矮小病和胸腺切除术后综合征中所观察到的情况。如果减少药物剂量,或者在注射时动物年龄较大,疾病的病程就会不那么严重。

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