SCHLESINGER M, MARK R
Science. 1964 Feb 28;143(3609):965-6. doi: 10.1126/science.143.3609.965.
A single injection of cortisol acetate into young mice induced a wasting syndrome similar to that observed in runt disease and in the post-thymectomy syndrome. The course of the disease was less severe if the dose of the drug was decreased or if the animals were older at the time of injection.
对幼鼠单次注射醋酸皮质醇会诱发一种消瘦综合征,类似于矮小病和胸腺切除术后综合征中所观察到的情况。如果减少药物剂量,或者在注射时动物年龄较大,疾病的病程就会不那么严重。