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[2型非复杂性糖尿病中抗凝血酶III和α-2-抗纤溶酶活性与其他止血参数的比较]

[Antithrombin III and alpha-2-antiplasmin activities compared with other hemostasis parameters in uncomplicated diabetes mellitus, type 2].

作者信息

Kotschy M, Drewniak W, Graczykowska-Koczorowska A, Listopadzki D

机构信息

Katedry i Zakładu Patofizjologii, Bydgoszczy.

出版信息

Pol Tyg Lek. 1992;47(1-2):17-8.

PMID:1409034
Abstract

In 40 patients with diabetes mellitus type II without clinical signs of any organ complications and in the respective control group the following indices of hemostasis were assessed: 1) activity of AI-III, 2) activity of alfa-2-AP, 3) fibrinogen, 4) time of fibrinolysis, 5) platelets count, adhesiveness and spontaneous aggregation, 6) kaolin-cephalin and profil stipven-cephalin plasma times. All these indices were normal in uncomplicated diabetes mellitus with the expectation of platelets activity. Stimulation of platelets activity and increase of corresponding parameters appears in diabetes mellitus type II before any other symptoms of angiopathy.

摘要

在40例无任何器官并发症临床体征的II型糖尿病患者及相应对照组中,评估了以下止血指标:1)抗凝血酶III活性;2)α2-抗纤溶酶活性;3)纤维蛋白原;4)纤溶时间;5)血小板计数、黏附性及自发聚集性;6)高岭土-脑磷脂和硅化脑磷脂血浆时间。除血小板活性外,所有这些指标在无并发症的糖尿病中均正常。在II型糖尿病中,在出现任何其他血管病变症状之前,血小板活性就会受到刺激,相应参数也会增加。

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