Arifkhanova S I, Ibragimov M A, Volkova E V
Probl Tuberk. 1992(5-6):41-5.
The paper deals with the results of a comparative morphologic, toxicologic and biochemical study of the character of reparative processes in destructive forms of pulmonary tuberculosis, specific features of non-coordination of collagen metabolism depending on the cumulation of organochlorine and organophosphorus pesticides and in the absence of their residual quantities in the patient's body on admission to a hospital and during current antibacterial therapy. The resected and removed lungs and blood of 1063 patients were used for the study. Specific features of a tuberculosis course, the duration and effectiveness of antibacterial therapy, the character of reparative processes, characteristic features of collagen metabolism and collagenosis, the character and dissemination of residual changes due to therapy were established in the compared groups of patients.
本文探讨了对1063例患者切除的肺组织及血液进行研究的结果，该研究涉及对肺结核破坏性形式的修复过程特征、取决于有机氯和有机磷农药累积情况以及患者入院时体内无残留量且在当前抗菌治疗期间的胶原代谢不协调的具体特征进行比较形态学、毒理学和生物化学研究。确定了不同组患者的肺结核病程特点、抗菌治疗的持续时间和有效性、修复过程的特征、胶原代谢和胶原病的特征、治疗引起的残留变化的特征和分布。
