NOBLE W C, WILLIAMS R E, JEVONS M P, SHOOTER R A
J Clin Pathol. 1964 Jan;17(1):79-83. doi: 10.1136/jcp.17.1.79.
The nasal carrier status of 3,736 patients was determined throughout their stay in hospital. The carrier rate on admission, which was highest in patients under 20 years of age, did not appear to vary with season.The carriage of strains resistant to penicillin increased with the patients' stay in hospital from 13.% on admission to 20.5% on discharge, and the acquisition of these strains was enhanced by the administration of antibiotics. Patients discharged from hospital carrying strains of staphylococci acquired in hospital lost them more readily than patients discharged carrying the strain which they had carried on admission, 31% of those discharged carrying strains resistant to penicillin and tetracycline being readmitted carrying these strains compared with 69% of those discharged carrying strains sensitive to these antibiotics.
在3736名患者住院期间,对他们的鼻腔带菌状态进行了测定。入院时的带菌率在20岁以下患者中最高,且似乎不受季节影响。对青霉素耐药菌株的携带率随患者住院时间的延长而增加,从入院时的13%增至出院时的20.5%,使用抗生素会增加这些菌株的获得。与携带入院时就已携带的菌株出院的患者相比,携带住院期间获得的葡萄球菌菌株出院的患者更容易失去这些菌株,携带对青霉素和四环素耐药菌株出院的患者中,31%再次入院时仍携带这些菌株,而携带对这些抗生素敏感菌株出院的患者中这一比例为69%。