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痛风

Gout.

作者信息

Leong K H, Feng P H

机构信息

Department of Rheumatology and Immunology, Tan Tock Seng Hospital, Singapore.

出版信息

Singapore Med J. 1992 Aug;33(4):393-4.

PMID:1411672
Abstract

Gout is a common disease in the primary health care setting. Diagnosis of primary gout is definite if urate crystals are present in synovial fluid or tophi. The colchicine therapeutic trial is a useful diagnostic aid but not specific. Secondary gout is associated with myeloproliferative disease. Non-steroidal anti-inflammatory agents or colchicine are the main stays of treatment in acute gouty arthritis. In the inter-critical period, uricosuric agents or allopurinol can be used to control hyperuricaemia. Allopurinol is the treatment of choice in secondary gout. Asymptomatic hyperuricaemia is not an indication for therapy.

摘要

痛风是基层医疗环境中的常见疾病。如果在滑液或痛风石中存在尿酸盐结晶,则原发性痛风的诊断明确。秋水仙碱治疗试验是一种有用的诊断辅助手段,但不具有特异性。继发性痛风与骨髓增殖性疾病相关。非甾体类抗炎药或秋水仙碱是急性痛风性关节炎的主要治疗药物。在发作间期,可使用促尿酸排泄药或别嘌醇来控制高尿酸血症。别嘌醇是继发性痛风的首选治疗药物。无症状性高尿酸血症不是治疗指征。

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