Vincent J B, Crowder M W, Averill B A
Department of Chemistry, University of Alabama, Tuscaloosa 35487.
Trends Biochem Sci. 1992 Mar;17(3):105-10. doi: 10.1016/0968-0004(92)90246-6.
Formation of phosphate esters by kinases has long been recognized as an important process in biochemistry, but the reverse reaction, hydrolysis of phosphate esters by phosphatases, has attracted less attention. Recent work suggests that phosphatases are as important as kinases in regulatory processes, and that they constitute a diverse group of enzymes that utilize a variety of chemical means to accelerate phosphate ester hydrolysis.
激酶形成磷酸酯的过程长期以来一直被认为是生物化学中的一个重要过程，但磷酸酶催化磷酸酯水解的逆反应却较少受到关注。最近的研究表明，磷酸酶在调节过程中与激酶同样重要，并且它们构成了一组多样的酶，利用各种化学手段加速磷酸酯的水解。
