Shigematsu A
Institute of Whole Body Metabolism, Chiba, Japan.
Yakubutsu Seishin Kodo. 1992 Aug;12(4):177-92.
Since Ullberg presented a macroautoradiograph showing the distribution of 35S-benzylpenicillin in rats by use of a commercial X-ray film in 1954, anything besides X-ray film has never been used for macroautoradiography. In the minireview a new type of radiation sensor, "Imaging Plate" (IP), is introduced as a useful sensor as a sensor that is more useful than previous ones. The IP is a photo-stimulable phosphor that can trap and store the radiation energy quantitatively. About 100 times higher sensitivity than any of ordinary X-ray films and very precise quantitativeness are demonstrated by many results reported recently. Simple procedures are herein presented with a few demonstrative examples of macro- and microautoradiography.
自1954年乌尔贝里使用商用X射线胶片展示了35S-苄青霉素在大鼠体内的分布的宏观放射自显影片以来，除X射线胶片外，从未有其他东西用于宏观放射自显影。在这篇简短的综述中，一种新型的辐射传感器“成像板”（IP）被作为一种比以前的传感器更有用的传感器引入。成像板是一种光激发磷光体，能够定量地捕获和存储辐射能量。最近报道的许多结果表明，其灵敏度比任何普通X射线胶片高约100倍，且具有非常精确的定量性。本文介绍了简单的操作步骤，并给出了一些宏观和微观放射自显影的示例。
