Futrell J M
Tulane University Medical School, Department of Dermatology, New Orleans, Louisiana 70112.
Am J Med Sci. 1992 Oct;304(4):261-7. doi: 10.1097/00000441-199210000-00008.
Loxoscelism, or envenomation by the brown recluse spider, may result in necrotic lesions and systemic reactions, including hemolytic anemia. Histologically, it resembles a cutaneous Arthus reaction. The reaction mechanism involves interactions between complement, neutrophils, and the clotting system. It is best treated with analgesics, avoidance of early surgical debridement, and oral dapsone.
褐蛛中毒，即被褐皮花蛛咬伤中毒，可能导致坏死性损伤和全身反应，包括溶血性贫血。从组织学上看，它类似于皮肤阿瑟斯反应。反应机制涉及补体、中性粒细胞和凝血系统之间的相互作用。最佳治疗方法是使用镇痛药、避免早期手术清创以及口服氨苯砜。
