Yuasa S, Bandai H, Yura T, Sumikura T, Takahashi N, Uchida K, Yamamoto N, Tanaka H, Aono M, Fujioka H
Second Department of Internal Medicine, Kagawa Medical School, Japan.
Am J Nephrol. 1992;12(1-2):111-5. doi: 10.1159/000168428.
A 45-year-old woman with a pheochromocytoma who had been on regular hemodialysis for 4 years and underwent successful surgery is described. Careful preoperative management, including the use of prazosin and weight control, was carried out to prevent severe intraoperative and postoperative cardiovascular complications. Prazosin was given at an initial dose of 0.5 mg/day, and the dosage was increased to 20 mg/day prior to surgery. The increase in intravascular volume led to a gain of 3 kg in body weight. No deterioration of the cardiovascular or respiratory function was caused by these maneuvers, and surgery was performed without significant complications except for a rapid rise of blood pressure during tumor resection. To our knowledge, only one similar case report could be found in the English literature.
本文描述了一名45岁患有嗜铬细胞瘤的女性患者,她接受定期血液透析4年并成功接受了手术。术前进行了仔细的管理,包括使用哌唑嗪和控制体重,以预防严重的术中及术后心血管并发症。哌唑嗪初始剂量为0.5毫克/天,术前剂量增加至20毫克/天。血管内容量增加导致体重增加3千克。这些措施未引起心血管或呼吸功能恶化,手术除肿瘤切除期间血压迅速升高外无明显并发症。据我们所知,英文文献中仅能找到一份类似病例报告。