Lindsay M K, Johnson N, Peterson H B, Willis S, Williams H, Klein L
Department of Gynecology and Obstetrics, Emory University, Atlanta, GA 30335.
Am J Obstet Gynecol. 1992 Oct;167(4 Pt 1):1096-9. doi: 10.1016/s0002-9378(12)80045-7.
The objective of our study was to describe the human immunodeficiency virus epidemic among pregnant adolescents undergoing follow-up in a large inner-city hospital.
We conducted a case-control study comparing demographic and risk behaviors of seropositive and seronegative adolescents (aged 13 to 20) identified from a population undergoing routine voluntary antibody screening at Grady Memorial Hospital in Atlanta, Georgia, between July 1987 and March 1991.
Of 10,794 pregnant adolescents screened, 51 (4.7/1000) were infected with human immunodeficiency virus. More than one fourth of case patients were < or = 17 years old. Significantly more case patients than controls reported a history of crack cocaine use (10 [19.6%] vs 23 [8.2%] p < 0.05). A majority (58.8%) of case patients reported no risk factors for infection, and the remainder (41.2%) were presumably infected by heterosexual contact. Thirty-nine controls (13.8%) had self-identified risk factors for infection.
Pregnant adolescents in our center are at risk for human immunodeficiency virus infection and should be targeted for human immunodeficiency virus education and risk reduction counseling.
我们研究的目的是描述在一家大型市中心医院接受随访的怀孕青少年中的人类免疫缺陷病毒流行情况。
我们进行了一项病例对照研究，比较了1987年7月至1991年3月期间在佐治亚州亚特兰大市格雷迪纪念医院接受常规自愿抗体筛查人群中，血清阳性和血清阴性青少年（年龄13至20岁）的人口统计学特征和风险行为。
在10794名接受筛查的怀孕青少年中，51人（4.7/1000）感染了人类免疫缺陷病毒。超过四分之一的病例患者年龄小于或等于17岁。报告有快克可卡因使用史的病例患者显著多于对照组（10人[19.6%]对23人[8.2%]，p<0.05）。大多数（58.8%）病例患者报告无感染风险因素，其余（41.2%）推测是通过异性接触感染。39名对照组患者（13.8%）有自我认定的感染风险因素。
我们中心的怀孕青少年有感染人类免疫缺陷病毒的风险，应将其作为人类免疫缺陷病毒教育和降低风险咨询的目标人群。
