Fonkalsrud E W, Ament M E, Vargas J
Division of Pediatric Surgery, UCLA School of Medicine 90024.
Am J Surg. 1992 Oct;164(4):327-31. doi: 10.1016/s0002-9610(05)80898-0.
Operative correction of symptomatic gastroesophageal reflux (GER) was undertaken in 530 children during a 21-year period. Gastroesophageal fundoplication (GEF) alone was performed in 415 children; 83 had simultaneous GEF and pyloroplasty; 13 had pyloroplasty alone; and 19 had GEF with later pyloroplasty. Of the last 355 children with reflux, 110 (31%) had pyloroplasty. Pyloroplasty was performed for persistent symptoms despite medical therapy when more than 60% of the isotope meal was retained in the stomach at 90 minutes. Children with central nervous system disorders and GER often had delayed gastric emptying (DGE). A modified Heineke-Mikulicz pyloroplasty was used for the first 59 children; the last 56 patients had a more simplified antroplasty with a 2.5- to 3.5-cm vertical incision through the antral muscularis down to the duodenum without mucosal incision; the muscularis was reapproximated in a transverse direction with sutures. With a mean follow-up of 5.8 years, only three patients experienced mild transient dumping. None had pyloroplasty leak or clinical evidence of alkaline reflux. Antroplasty is a helpful, simple adjunct to GEF with low morbidity in children with GER and DGE.
在21年的时间里,对530名儿童进行了有症状的胃食管反流(GER)的手术矫正。415名儿童仅进行了胃食管胃底折叠术(GEF);83名儿童同时进行了GEF和幽门成形术;13名儿童仅进行了幽门成形术;19名儿童先进行了GEF,后来又进行了幽门成形术。在最后355名反流儿童中,110名(31%)进行了幽门成形术。当90分钟时同位素餐留在胃内的比例超过60%,尽管进行了药物治疗但仍有持续症状时,进行幽门成形术。患有中枢神经系统疾病和GER的儿童经常有胃排空延迟(DGE)。前59名儿童采用改良的海涅克-米库利兹幽门成形术;最后56名患者采用了更简化的胃窦成形术,通过胃窦肌层做一个2.5至3.5厘米的垂直切口直至十二指肠,不切开黏膜;肌层用缝线横向重新缝合。平均随访5.8年,只有3名患者出现轻度短暂倾倒综合征。没有患者出现幽门成形术渗漏或碱性反流的临床证据。胃窦成形术是GEF的一种有用、简单的辅助手术,在患有GER和DGE的儿童中发病率低。