Perrin C, Lacour J P, Michiels J F, Flory P, Ziegler G, Ortonne J P
Department of Pathology, University of Nice, France.
Am J Dermatopathol. 1992 Oct;14(5):418-25.
A case of multicentric reticulohistiocytosis is presented with extensive immunohistochemical study of the infiltrate in both paraffin and cryostat sections. Factor XIIIa dermal dendrocyte marker was demonstrated in the cytoplasm of histiocytes, which has not been reported previously in this disease. In addition, the S100 protein stained positive. This immunophenotyping study suggests a dermal dendrocyte lineage with an unusual expression of S100 protein.
本文报告1例多中心性网状组织细胞增生症,并对石蜡切片和冰冻切片中的浸润物进行了广泛的免疫组织化学研究。在组织细胞的细胞质中证实有ⅩⅢa因子真皮树突状细胞标记物,这在该疾病中此前尚未见报道。此外,S100蛋白染色呈阳性。这项免疫表型研究提示为具有S100蛋白异常表达的真皮树突状细胞谱系。